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BOC Sciences Announced That It Will Participate in TIDES USA 2021 in September

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BOC Sciences Announced That It Will Participate in TIDES USA 2021 in September

August 06
21:50 2021

New York, USA – August 6, 2021 – Recently, BOC Sciences announced that it has registered to participate in the 2021 TIDES USA conference to meet more professionals in the PseudoUridine industry and seek business cooperation.

TIDES USA (Oligonucleotide & Peptide Therapeutics Conference) is the world’s largest gathering of those interested in accelerating the development and commercialization of oligonucleotides, peptides, mRNA and genome editing products from early discovery to later stages. Every year, TIDES’s scientific agenda includes more than 150 top scientists in the industry, and showcases the latest scientific and industry updates in the entire field from discovery, preclinical and clinical development to CMC, manufacture and commercialization of therapeutic drugs and vaccines for oligos, peptides, mRNA and genome editing products.

BOC Sciences has become the world’s largest supplier of PseudoUridine with the largest production capacity. The current annual output of PseudoUridine exceeds 500 kilograms. It is worth noting that the high-purity PseudoUridine provided by BOC Sciences has been used as a raw material for the SARS-CoV-2 mRNA vaccine, which solves the problem of insufficient raw materials during the initial vaccine development.

In addition to PseudoUridine, BOC Sciences also provides a wealth of PseudoUridine derivatives, which can be divided into the four categories: Modified PseudoUridine, Phosphate PseudoUridine, Phosphoramidite PseudoUridine, Isotope-labeled PseudoUridine.

Modified PseudoUridine

Modified nucleotides are found in almost all kinds of natural RNA. There are about 100 different base modifications known, and they can perform multiple functions. PseudoUridine (CAS 1445-07-4), called the fifth RNA residue, is the most common modification in RNA. PseudoUridine is commonly found in ribosomal RNA (rRNA) and is ubiquitous in transfer RNA (tRNA), small nuclear RNA (snRNA), and other non-coding RNA (ncRNA). Recently, the importance of PseudoUridine in the epigenetic regulation of mRNA function has become increasingly apparent.

Phosphate PseudoUridine

Phosphate PseudoUridine is usually produced by the phosphorylation occurring in the 5′-position hydroxyl group of ribose of PseudoUridine. Phosphate PseudoUridine is a C-nucleotide, in which the uracil part binds to the sugar through its carbon atom instead of a nitrogen atom to form a C-C glycosidic bond. PseudoUridine phosphate can be divided into PseudoUridine 5′-monophosphate (ΨMP), PseudoUridine 5′-diphosphate (ΨDP) and PseudoUridine 5′-triphosphate (ΨTP) according to the number of connected phosphates.

Phosphoramidite PseudoUridine

Phosphoramidites are used as building blocks in the chemical synthesis of oligonucleotides. PseudoUridine phosphoramidite can help introduce PseudoUridine into RNA oligonucleotides. PseudoUridine phosphoramidite allows efficient and reliable synthesis of RNA containing single or multiple PseudoUridine modifications. PseudoUridine modified mRNA has shown promising therapeutic potential in gene replacement and vaccination.

Isotope-labeled PseudoUridine

PseudoUridine can be labeled with 15N stable isotope at helix 69 of E. coli 23S rRNA, which may help to study the kinetics and interaction of this RNA fragment with ribosomes or separation ligands. These labeled nucleosides are important for exploring the biological effects of PseudoUridine and 3-methylPseudoUridine (CAS 81691-06-7).

BOC Sciences’s booth number at TIDES USA is #874. And the company recently stated that it hopes to share more information about its pseudoadenosine production with other participants at the exhibition and seek more commercial cooperation opportunities.

For more information about BOC Sciences’s participation in this event, please visit the website: https://informaconnect.com/tides/sponsors/boc-sciences.

About BOC Sciences

BOC Sciences has professional experts who focus on research in many fields such as pharmaceuticals, chemistry, and life sciences, providing high-quality products and services for scientists and researchers in the global academic and industrial circles. This company has become the world’s leading supplier of PseudoUridine with the largest production capacity.

Media Contact
Company Name: BOC Sciences
Contact Person: Alex Brown
Email: Send Email
Phone: 1-631-485-4226
Country: United States
Website: https://nucleotech.bocsci.com

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